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Characterization of Micro-Features in Polymeric Drug Delivery Devices Using FDM

[+] Author Affiliations
S. H. Masood, Shivdeep Singh

Swinburne University of Technology, Hawthorn, VIC, Australia

Paper No. IMECE2007-43298, pp. 463-470; 8 pages
doi:10.1115/IMECE2007-43298
From:
  • ASME 2007 International Mechanical Engineering Congress and Exposition
  • Volume 3: Design and Manufacturing
  • Seattle, Washington, USA, November 11–15, 2007
  • Conference Sponsors: ASME
  • ISBN: 0-7918-4297-5 | eISBN: 0-7918-3812-9
  • Copyright © 2007 by ASME

abstract

This paper presents the results of the experimental work done in applying the Fused Deposition Modelling (FDM) rapid prototyping technique to fabricate and characterise the porous polymeric matrix for controlled drug delivery device (DDD). With FDM technique, both macro and micro level structures of the device matrix can be produced and controlled, which provide several advantages over the conventional techniques of DDD fabrication. The paper investigates effect of various FDM parameters viz. Raster Width, Contour Width, Air-gap and Raster Angle on the controlled drug release profiles, drug infiltration and porosity of fabricated device matrices. The paper concludes that effective DDD matrices with desired release regimes can be fabricated using FDM technology with careful selection of FDM control parameters.

Copyright © 2007 by ASME

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