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Identification of Compensatory Arterial Dynamics in Swine Using a Non-Invasive Sensor for Local Vascular Resistance

[+] Author Affiliations
Lu Wang, Sardar Ansari, Kevin R. Ward, Kayvan Najarian, Kenn R. Oldham

University of Michigan, Ann Arbor, MI

Paper No. DSCC2018-9063, pp. V001T14A002; 7 pages
  • ASME 2018 Dynamic Systems and Control Conference
  • Volume 1: Advances in Control Design Methods; Advances in Nonlinear Control; Advances in Robotics; Assistive and Rehabilitation Robotics; Automotive Dynamics and Emerging Powertrain Technologies; Automotive Systems; Bio Engineering Applications; Bio-Mechatronics and Physical Human Robot Interaction; Biomedical and Neural Systems; Biomedical and Neural Systems Modeling, Diagnostics, and Healthcare
  • Atlanta, Georgia, USA, September 30–October 3, 2018
  • Conference Sponsors: Dynamic Systems and Control Division
  • ISBN: 978-0-7918-5189-0
  • Copyright © 2018 by ASME


Autoregulatory dynamics of the cardiovascular system play an important role in maintaining oxygenated blood transportation throughout the human body. In this work, a feedback dynamics model of the cardiovascular system with respect to heartrate and peripheral vascular resistance effects on longer-term blood pressure changes in the systemic circulation is presented. The model is identified from data taken from a swine test subject, instrumented in part with a wearable, non-invasive sensor for estimating peripheral arterial radius. Comparative simulations for the open and close loop model highlight significantly changed hemodynamics after hemorrhage.

Copyright © 2018 by ASME



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