Full Content is available to subscribers

Subscribe/Learn More  >

Evaluation of Pulmonary Arterial Hypertension Using Computational Fluid Dynamics Simulation

[+] Author Affiliations
Shahab Taherian, Hamid Rahai, Jamie Shin

California State University, Long Beach, CA

Jeremy Feldman

Arizona Pulmonary Specialists, Phoenix, AZ

Thomas Waddington

Mount Nittany Health, State College, PA

Paper No. IMECE2017-70193, pp. V003T04A050; 7 pages
  • ASME 2017 International Mechanical Engineering Congress and Exposition
  • Volume 3: Biomedical and Biotechnology Engineering
  • Tampa, Florida, USA, November 3–9, 2017
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-5836-3
  • Copyright © 2017 by ASME


In silico study of the relationships between flow conditions, arterial surface shear stress, and pressure was investigated in a patient with pulmonary arterial hypertension (PAH), using multi-detector Computed Tomography Angiography (CTA) images and Computational Fluid Dynamics (CFD). The CTA images were converted into 3D models and transferred to CFD software for simulations, allowing for patient-specific comparisons between in silico results with clinical right heart catheterization pressure data. The simulations were performed using two different methods of outlet boundary conditions: zero traction and lumped parameter model (LPM) methods. Outlet pressures were set to a constant value in zero traction method, which can produce flow characteristics solely based on the segmented distal arteries, while the lumped parameter model used a three-element Windkessel lumped model to represent the distal vasculature by accounting for resistance, compliance, and impedance of the vasculature. Considering existing limitations with both approaches, it was found that the lumped parameter Windkessel outlet boundary condition provides a better correlation with the clinical RHC pressure results than the zero traction constant pressure outlet boundary condition.

Copyright © 2017 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In