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Measurement of Glioma Viscoelasticity Using a Handheld Palpation Imitation Device

[+] Author Affiliations
Shigeto Hayashi

Hyogo Emergency Medical Center, Chuo-ku, Japan

Atsushi Sakuma

Kyoto Institute of Technology, Matsugasaki, Japan

Takashi Sasayama, Eiji Kohmura

Kobe University, Chuo-ku, Japan

Paper No. IMECE2017-70835, pp. V003T04A008; 4 pages
  • ASME 2017 International Mechanical Engineering Congress and Exposition
  • Volume 3: Biomedical and Biotechnology Engineering
  • Tampa, Florida, USA, November 3–9, 2017
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-5836-3
  • Copyright © 2017 by ASME


We examined glioma tissues immediately after en-bloc removal during surgery and measured elastic modulus, viscosity, and viscoelasticity of the gray and white matter to confirm the feasibility of measurement using an indentation device. Measurements were obtained from excised parenchymal brain tumor tissue of four adult patients. The white matter exhibited higher elastic modulus than the gray matter in all patients. Viscoelasticity analysis was performed in two patients, with viscoelastic behavior observed in the white but not in the gray matter in both patients. The loss of viscoelasticity in the white matter observed in one patient may be related to the calcification visible in the preoperative computed tomography image.

Copyright © 2017 by ASME
Topics: Viscoelasticity



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