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Evaluation of Paravalvular Leakage in Novel Mechanical Heart Valve

[+] Author Affiliations
Ankit Saxena

Innovator Lab Consultants India Pvt. Ltd., New Delhi, India

Rohan Shad

University College of Medical Sciences, New Delhi, India

Mrudang Mathur, Anwesha Chattoraj

Delhi Technological University, New Delhi, India

Sujay Shad

Sir Ganga Ram Hospital, New Delhi, India

Paper No. DETC2017-67729, pp. V003T13A007; 5 pages
  • ASME 2017 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference
  • Volume 3: 19th International Conference on Advanced Vehicle Technologies; 14th International Conference on Design Education; 10th Frontiers in Biomedical Devices
  • Cleveland, Ohio, USA, August 6–9, 2017
  • Conference Sponsors: Design Engineering Division, Computers and Information in Engineering Division
  • ISBN: 978-0-7918-5815-8
  • Copyright © 2017 by ASME


We developed a new mechanical heart valve prototype with a unique mechanism for attachment to cardiac tissue. The development of novel prosthetic heart valve systems requires careful assessment of paravalvular leaks — leakage of fluid that takes place between the valve and the cardiac tissue it is attached to. Traditional methods of testing paravalvular leaks in flow chambers are not ideal for novel devices and may underestimate its true extent. In this paper we developed a novel method of quantifying paravalvular leaks involving the use of 3D printed prototype heart valves and cadaveric bovine hearts, and compared the results with those from commercially available Medtronic ATS mechanical bileaflet valves. The average leak in our final prototype heart valves were found to be 0.13 ml/sec, compared to 0.33 ml/sec in the ATS valve.

Copyright © 2017 by ASME



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