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Hierarchical Engineering Model of the Human Body

[+] Author Affiliations
Somayajulu D. Karamchetty

Technology Consultant, Potomac, MD

Paper No. IMECE2016-66253, pp. V003T04A060; 6 pages
  • ASME 2016 International Mechanical Engineering Congress and Exposition
  • Volume 3: Biomedical and Biotechnology Engineering
  • Phoenix, Arizona, USA, November 11–17, 2016
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-5053-4
  • Copyright © 2016 by ASME


Engineers and scientists are able to understand and analyze the behavior of complex engineering systems in a wide range of critical technologies through hierarchical modeling followed by simulation of the model operation. This process results in a high fidelity integrated model as each level in the hierarchy is modeled in sufficient detail.

The overall objective of this effort is to develop a sophisticated hierarchical model of the human body, followed by simulation of the model operation. In this initial research phase, the feasibility of the concept is explored and a framework for the model is described. A six-level model consisting of the whole body as a system, system of systems, organs, tissues, cells, and molecules is proposed and described. This paper explains that the human body is amenable to such hierarchical modeling and describes the benefits that can be achieved.

The systems in the body deal with numerous processes: electrical, chemical, biochemical, energy conversion, transportation, pumping, sensing, communications, and so on. Control volume models for the organs in the body capture the mass and energy balance and chemical reactions. Tissue can be represented similar to structural components made of various biomaterials. Cells can be represented as a manufacturing and maintenance workforce assisted by molecular reactions.

Following the representation of a healthy body, simulation runs by inserting faults and/or deficiencies in the operational parameters into the model could reveal the causes for specific diseases and illnesses. Such modeling and simulation will benefit medical, pharmaceutical, nutritional specialists, and engineers in designing, developing, and delivering products and services to enable humans to lead healthy lives.

Copyright © 2016 by ASME



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