Full Content is available to subscribers

Subscribe/Learn More  >

Vortex Dynamics of Ruptured and Unruptured Intracranial Aneurysms

[+] Author Affiliations
Nicole Varble, Gabriel Trylesinski, Jianping Xiang, Hui Meng

State University of New York at Buffalo, Buffalo, NY

Paper No. DETC2014-35713, pp. V003T12A015; 2 pages
  • ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference
  • Volume 3: 16th International Conference on Advanced Vehicle Technologies; 11th International Conference on Design Education; 7th Frontiers in Biomedical Devices
  • Buffalo, New York, USA, August 17–20, 2014
  • Conference Sponsors: Design Engineering Division, Computers and Information in Engineering Division
  • ISBN: 978-0-7918-4634-6
  • Copyright © 2014 by ASME


Intracranial aneurysms are a potentially devastating pathological dilation of brain arteries that affect 1–5 % of the population. In this study we investigated the vortex structures of both unruptured and ruptured intracranial aneurysms as a discriminating property. We performed pulsatile computational fluid dynamic simulations on 204 patient-specific aneurysm models (57 ruptured and 147 unruptured) derived from patient angiographic imaging. Using Q-criterion we analyzed the coherent structures both throughout the aneurysm volume and at the wall. The relative surface area with positive Q values (indicating vortices at the wall) was able to differentiate ruptured and unruptured aneurysms. For the first time, in a large patient cohort, mechanistic fluid analysis is leading to insights into rupture pathways.

Copyright © 2014 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In