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Size-Dependent Antibacterial Behavior of Graphene Quantum Dots

[+] Author Affiliations
Siheng Su, Carla B. Shelton, Jingjing Qiu

Texas Tech University, Lubbock, TX

Paper No. IMECE2013-64872, pp. V015T16A006; 4 pages
  • ASME 2013 International Mechanical Engineering Congress and Exposition
  • Volume 15: Safety, Reliability and Risk; Virtual Podium (Posters)
  • San Diego, California, USA, November 15–21, 2013
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-5644-4
  • Copyright © 2013 by ASME


In this study, the antibacterial behavior of differing sized graphene quantum dots (GQDs) was studied. The gram negative bacteria, Escherichia coli (E. coli), were used as the bacteria mode. Different sized GQDs with tunable fluorescent colors were acquired by a gel-filtration method. The size, surface chemistry, and photoluminescence properties of GQDs were characterized, respectively. The viability of GQDs treated bacteria was determined by the standard plate counting method. Moreover, the reactive oxidative species (ROS) level was detected by the 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) method. The integrality of the bacteria membrane was observed under the scanning electron microscopy (SEM). The experimental results indicated that GQDs demonstrated size-dependent and surface chemistry-dependent antibacterial behaviors. This research provided insightful guidelines in the selection of suitable GQDs for their potential bioapplications.

Copyright © 2013 by ASME



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