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Modelling Dynamical Arterial Adaptations to Altered Chemo-Mechanical Environments

[+] Author Affiliations
Luca Cardamone

Università di Salerno, Fisciano, Italy

Arturo Valentin, Jay D. Humphrey

Texas A&M University, College Station, TX

Paper No. SBC2008-192097, pp. 927-928; 2 pages
  • ASME 2008 Summer Bioengineering Conference
  • ASME 2008 Summer Bioengineering Conference, Parts A and B
  • Marco Island, Florida, USA, June 25–29, 2008
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4321-5
  • Copyright © 2008 by ASME


Vascular smooth muscle cells (SMC), endothelial cells (EC), and fibroblasts exist in a dynamic mechanical environment and can sense and respond to mechanical stimuli in vivo (McKnight and Frangos [1]). It is becoming more and more clear that complex dynamics not only influences vascular tone but also SMC proliferation (see Dancu et al. [2]) and extracellular matrix turnover (Cummins et al. [3]) by stimulating cell activity.

Copyright © 2008 by ASME



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