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Correlation Between Nanoindentation Modulus and Mineral Density in Fracture Callus Tissues

[+] Author Affiliations
Pui Leng Leong, Elise F. Morgan

Boston University, Boston, MA

Paper No. SBC2008-193149, pp. 675-676; 2 pages
  • ASME 2008 Summer Bioengineering Conference
  • ASME 2008 Summer Bioengineering Conference, Parts A and B
  • Marco Island, Florida, USA, June 25–29, 2008
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4321-5
  • Copyright © 2008 by ASME


The stiffness and strength of a healing bone fracture depend on the geometry of the fracture callus as well as the mechanical properties of the callus tissues. In the clinical setting, the mechanical stability of a healing fracture is often estimated qualitatively based on the radioopacity of the callus tissue. However, a quantitative association between tissue mineralization and mechanical properties has yet to be established for these tissues. Quantifying callus tissue material properties and mineral content may therefore enable improved non-invasive assessments of bone healing. In addition, elucidating relationships between callus tissue composition and function will provide a means of understanding the mechanism by which the injured bone recovers its mechanical integrity.

Copyright © 2008 by ASME



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