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Hemodynamic Energy Dissipation in the Cardiovascular System: Generalized Theoretical Analysis on Disease States

[+] Author Affiliations
Lakshmi P. Dasi, Kartik S. Sundareswaran, Diane de Zelicourt, Resmi Krishnankutty, Ajit P. Yoganathan

Georgia Institute of Technology, Atlanta, GA

Kerem Pekkan

Carnegie Mellon University, Pittsburgh, PA

Pedro J. del Nido

Harvard University, Children’s Hospital, Boston, MA

Paper No. SBC2008-192936, pp. 47-48; 2 pages
  • ASME 2008 Summer Bioengineering Conference
  • ASME 2008 Summer Bioengineering Conference, Parts A and B
  • Marco Island, Florida, USA, June 25–29, 2008
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4321-5
  • Copyright © 2008 by ASME


Independent of the disease type, high hemodynamic energy dissipation in the circulation always impacts the pumping ventricle that, often always resulting in chronic heart failure as a secondary disease. For aortic stenosis, which is an arterial disease, an index based on total pressure (static plus dynamic) loss, which is a pseudo indicator of energy dissipation based on Bernoulli’s Equation, is widely used, while raw energy loss has been proposed to assess the severity of the Fontan connections clinically. Both diseases have separate frameworks for hemodynamic assessment of the respective dissipative lesions.

Copyright © 2008 by ASME



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