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A Finite Element Prediction of Cellular Strain in a GAG-Scaffold

[+] Author Affiliations
A. J. F. Stops, D. O’Mahoney, P. E. McHugh

National University of Ireland, Galway, Ireland

L. A. McMahon, P. J. Prendergast

Trinity College, Dublin, Ireland

Paper No. SBC2007-176147, pp. 989-990; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


Tissue engineering is an emerging area in bioengineering engaging biomaterials, biology and biomechanics. Current in-vitro studies have shown mesenchymal differentiation into specific cellular lineages when using osteoinductive factors [1], though the quantitative understanding of the load transfer process within a cell-seeded scaffold is still relatively unknown. Here, this paper presents a finite element simulation of the cellular-scaffold interaction so that cellular strain and the corresponding strain mechanisms can be evaluated.

Copyright © 2007 by ASME



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