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Voluntary Running Exercise Ameliorates Muscle Loss in Mice

[+] Author Affiliations
Andrea M. Hanson, Louis S. Stodieck, Virginia L. Ferguson

University of Colorado, Boulder, CO

Paper No. SBC2007-176739, pp. 969-970; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


Both spaceflight and bed rest studies are known to cause substantial muscle loss in humans. Of particular interest in atrophy studies is the postural, slow-twitch fiber soleus muscle. It has been demonstrated that during periods of disuse, slow-twitch fibers undergo fiber type switching and morph into fast-twitch fibers [1]. Alternatively, when exercise is prescribed, there is switching of fast-to slow-twitch fibers [2], indicating a profound adaptability of the muscle to exercise.

Copyright © 2007 by ASME
Topics: Muscle



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