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Micro-CT-Based Large Scale Linear Finite Element Models Predict the Strength of Human Thoracic and Lumbar Vertebral Bodies

[+] Author Affiliations
Yener N. Yeni, Do-Gyoon Kim, Roger R. Zauel

Henry Ford Hospital, Detroit, MI

Evan M. Johnson, Dianna D. Cody

The University of Texas, Houston, TX

Paper No. SBC2007-176699, pp. 965-966; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


Vertebral fractures are among the most common and debilitating fractures. Structural organization of cancellous and cortical bone in a vertebra and their local properties are important factors that determine the strength of a vertebra. Linear finite element models utilizing Quantitative Computed Tomography (QCT) images have proven useful for predicting vertebral strength and are potentially useful in predicting risk of fracture in a clinical setting [1]. However, the amount of architectural detail in these models is not sufficient for studying trabecular stress and strains, and their relationship with the microscopic structure, which is important for understanding the mechanisms behind vertebral fragility.

Copyright © 2007 by ASME



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