Full Content is available to subscribers

Subscribe/Learn More  >

Quantifying Variations in Collagen Matrix Deformation in Loaded Articular Cartilage

[+] Author Affiliations
Paul Briant, Thomas P. Andriacchi

Stanford University, Stanford, CAVeterans Affairs Palo Alto, Palo Alto, CA

Scott Bevill

Stanford University, Stanford, CA

Paper No. SBC2007-176518, pp. 931-932; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


Mechanical loads have been shown in numerous studies to affect the health of articular cartilage [1]. Regional variations in the local deformation within articular cartilage under both normal and abnormal loading are, however, poorly understood. Understanding these deformation patterns is important, since conditions such as anterior cruciate ligament injury have been suggested to initiate cartilage breakdown by shifting the regions of frequent loading within the joint [2]. Quantifying variations in the deformation behavior of the collagen matrix in cartilage under load will therefore provide insight into the mechanical environment within cartilage and test the feasibility of a kinematic pathway to the initiation of osteoarthritis (OA). The objective of this study was to test the hypothesis that the collagen matrix in two regions of cartilage that normally experience different applied loads will deform differently under the same applied load.

Copyright © 2007 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In