Full Content is available to subscribers

Subscribe/Learn More  >

The Characterization of Age-Related Human Cortical Bone Porosity, Water Distribution Changes by Nuclear Magnetic Resonance

[+] Author Affiliations
Qingwen Ni

Southwest Research Institute, San Antonio, TXTexas A&M International University, Laredo, TX

Juffry S. Nyman, Xiaodu Wang

University of Texas at San Antonio, San Antonio, TX

Daniel P. Nicolella

Southwest Research Institute, San Antonio, TX

Paper No. SBC2007-176213, pp. 7-8; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


Previous studies have shown that bone fracture toughness is also significantly correlated to changes in porosity, microarchitecture, osteonal morphology, collagen integrity, microdamage, and the interactions of water with collagen and mineral phases, all of which are measures of bone quality. Currently, the influence of water removal on the strength and toughness of cortical bone has studied by Nyman et al [1]. The results have shown that loss of water in the collagen phase decreases the toughness of bone, whereas loss of water associated with the mineral phase decreases both bone strength and toughness. However, in that paper the loss of water was used the dehydration method for such mechanism studies. Here, we hypothesize that the NMR relaxation technique can non-destructively and non-invasively assess the porosity, bound water (water bound to collage and mineral phases) and mobile water (water within the pores).

Copyright © 2007 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In