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Determination of Real Time In-Vivo Cartilage Contact Deformation in the Ankle Joint

[+] Author Affiliations
Guoan Li, Michal Kozanek

Massachusetts General Hospital/Harvard Medical School, Boston, MA

Lu Wan

Massachusetts General Hospital/Harvard Medical School, Boston, MAMassachusetts Institute of Technology, Cambridge, MA

Paper No. SBC2007-175319, pp. 541-542; 2 pages
doi:10.1115/SBC2007-175319
From:
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME

abstract

Knowledge of in-vivo articular cartilage contact deformation is critical for understanding normal cartilage function and the etiology of osteoarthritis (2,8). This knowledge is also instrumental for design of ex-vivo experiment to investigate the chondrocyte mechanotransductions under physiological loading conditions (7). Further, in-vivo cartilage contact data is necessary for validation of 3D computational models used to predict biomechanical responses of the articular joints (1,5). However, due to the complexity of in-vivo joint loading conditions as well as the complicated joint geometry, little information is available on in-vivo cartilage deformation in literature (9). In-vivo cartilage deformation as a function of loading history has not been delineated.

Copyright © 2007 by ASME

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