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Simulation of Blood Perfusion in Tumour Microvasculature

[+] Author Affiliations
Jie Wu, Shixiong Xu, Gaiping Zhao

Fudan University, Shanghai, China

Quan Long, Michael W. Collins, Carola S. Koenig

Brunel University, Uxbridge, Middlesex, UK

Yuping Jiang

Huashan Hospital, Shanghai, China

Anwar R. Padhani

Mount Vernon Hospital, Northwood, Middlesex, UK

Paper No. SBC2007-176335, pp. 483-484; 2 pages
doi:10.1115/SBC2007-176335
From:
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME

abstract

Solid tumor has become one of the most serious diseases that threaten mankind’s health and life all over the world. It is well recognized that structural and functional abnormalities of tumor vascularity and the subsequent microenvironment and cellular adaptive consequences creates a great barrier for drug delivery in solid tumors, contributing to treatment resistance. Hence, the investigation of microcirculatory dynamics in solid tumors has important significance for improving the effectiveness of many anticancer therapies.

Copyright © 2007 by ASME
Topics: Simulation , Blood , Tumors

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