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Geometry Anticipates Hemodynamic Phenotype of Basilar Tip Aneurysms

[+] Author Affiliations
Matthew D. Ford, David W. Holdsworth

Robarts Research Institute, London, ON, CanadaThe University of Western Ontario, London, ON, Canada

Sang-Wook Lee

University of Toronto, Toronto, ON, Canada

Stephen P. Lownie

Robarts Research Institute, Toronto, ON, CanadaThe University of Western Ontario, London, ON, Canada

David A. Steinman

Robarts Research Institute, London, ON, CanadaThe University of Western Ontario, London, ON, CanadaUniversity of Toronto, London, ON, Canada

Paper No. SBC2007-171979, pp. 449-450; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


The prevalence of unruptured cerebral aneurysms is estimated to be as high as 5% [1]. Basilar tip aneurysms account for 4–5% of these, but have a higher risk of rupture [2]. They are also difficult to treat surgically, and so endovascular therapy is often the only option. Hemodynamic forces have been implicated in the risk of rupture [3] and complications of endovascular therapy [4]; however, hemodynamic information is difficult to acquire clinically. Computational fluid dynamics (CFD), in combination with clinical imaging, can be used to accurately capture the intra-aneurysmal hemodynamics in a patient-specific manner [5]. Still, these techniques have not translated to routine clinical use, largely due to the time and effort required to construct, simulate, and interpret these models.

Copyright © 2007 by ASME



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