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The Effect of Permeability of Cartilage Superficial Zone on the Behavior of Stress Relaxation and Creep of Human Ankle Joint

[+] Author Affiliations
Lu Wan

Massachusetts General Hospital/Harvard Medical School, Boston, MAMassachusetts Institute of Technology, Cambridge, MA

Guoan Li

Massachusetts General Hospital/Harvard Medical School, Boston, MA

Paper No. SBC2007-176175, pp. 353-354; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


The microstructure of articular cartilage could be divided into four distinct zones: the superficial zone, middle zone, deep zone, and calcified cartilage zone. It is believed that the superficial zone of articular cartilage has a lower permeability, which may be related to the close packing of the collagen fibrils resulting in a system of much narrow channels which offer a greater resistance to flow [1]. This parametric study investigated the influence of permeability of the superficial zone on the behavior of cartilage stress relaxation and creep of human ankle joint using a 2D biphasic poroelastic finite element model (FEM) that was created from a living human ankle joint.

Copyright © 2007 by ASME



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