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A Structural, Kinetic Model of Soft Tissue Thermomechanics

[+] Author Affiliations
Triantafyllos Stylianopoulos, Alptekin Aksan, Victor H. Barocas

University of Minnesota, Minneapolis, MN

Paper No. SBC2007-176008, pp. 331-332; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


Sub-ablative heating of collagenous soft tissues is central to thermal therapies such as thermal capsulorrhaphy, thermokeratoplasty and skin resurfacing [1]. These therapies target the heat-induced denaturation of the collagen molecule, which starts in a temperature range of 55–75 °C. There are relatively few theoretical studies describing the heat-induced alterations in soft tissues, which are mainly phenomenological [2]. In this work, a methodology for studying the kinetics of soft tissue thermomechanics is presented and used to predict the thermal response of New Zealand white patellar tendons [3]. The modeling approach accounts for the microstructure of the tissue and utilizes information at the single-molecule level to obtain the macroscopic response.

Copyright © 2007 by ASME



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