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Effect of the Red Blood Cells on the Primary Thrombus Formation

[+] Author Affiliations
Koichiro Yano

Toyota Motor Corporation, Toyota, Aichi, Japan

Daisuke Mori, Ken-ichi Tsubota, Takuji Ishikawa, Takami Yamaguchi

Tohoku University, Sendai, Miyagi, Japan

Shigeo Wada

Osaka University, Toyonaka, Osaka, Japan

Paper No. SBC2007-176360, pp. 289-290; 2 pages
doi:10.1115/SBC2007-176360
From:
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME

abstract

It has been pointed out that some mechanical factors play important roles in a series of physiological or biochemical processes during the thrombus formation. Recently, many studies including the authors’ work qualitatively demonstrated how the thrombus is regulated under the influences of the blood flow and the intercellular molecular bridge using computational fluid dynamics techniques[1–4]. They verified the importance of the balance of them in the process of the thrombus formation. However, few studies have taken into account the existence of the other cell constituents than the platelet such as red blood cell (RBC).

Copyright © 2007 by ASME

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