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Collocation of Macrophages and Mechanical Stress in Human Coronary Atherosclerotic Plaque

[+] Author Affiliations
K. Melissa Hallow, Peter C. Carnell, Raymond P. Vito

Georgia Institute of Technology, Atlanta, GA

W. Robert Taylor

Emory University, Atlanta, GA

Paper No. SBC2007-176528, pp. 213-214; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


Cardiovascular disease (CVD) is the leading cause of death in the United States. One of the primary causes of CVD is atherosclerosis, a progressive disease that begins with the deposition of lipid on arterial walls to form plaque. Over time, some plaques progress to an unstable configuration that is vulnerable to rupture, while others remodel to more stable configurations. The factors directing plaque progression toward instability are poorly understood.

Copyright © 2007 by ASME



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