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Effects of Reduced Compliance on Endothelial Functionality With Regards to Inflammation and Adhesion

[+] Author Affiliations
Tyler N. Thacher, Veronica Gambillara, Rafaela da Silva, Paolo Silacci, Nikos Stergiopulos

Swiss Federal Institute of Technology, Lausanne, Switzerland

Paper No. SBC2007-176130, pp. 165-166; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


Among other things, the aging process is associated with a stiffening of the arteries, initiating the development of systolic hypertension and a significant increase in pulse pressure. Amplified pulse pressure has been linked to problems causing arterial dysfunction. In this study we focused on how reduced wall compliance induces pulse pressure-mediated changes in endothelial function with regards to inflammation and adhesion.

Copyright © 2007 by ASME
Topics: Adhesion



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