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Fiber-Based Constitutive Model of Myocardial Scar Tissue

[+] Author Affiliations
Dezba G. Coughlin, Gregory M. Fomovsky, Jeffrey W. Holmes

Columbia University, New York, NY

Paper No. SBC2007-176098, pp. 157-158; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


It has largely been accepted that collagen fibers play an important role in the mechanics of myocardial scar tissue; however, few studies have performed both mechanical and structural analysis on the same samples to confirm this. Therefore, the goal of this study was to combine both types of analysis with a structure-based constitutive model, which incorporates measured collagen fiber orientations, to gain a better understanding of the structural basis for the mechanics of two-week-old scar tissue.

Copyright © 2007 by ASME



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