Full Content is available to subscribers

Subscribe/Learn More  >

Different Strains of Mice Exhibit Different Aortic Arch Geometry and Plaque Distribution: A Fluid Dynamic Effect

[+] Author Affiliations
Hui Zhu, Jessica Shih, David S. Long, Morton H. Friedman

Duke University, Durham, NC

John R. Hagaman, Nobuyo Maeda

University of North Carolina at Chapel Hill, Chapel Hill, NC

Paper No. SBC2007-175844, pp. 151-152; 2 pages
  • ASME 2007 Summer Bioengineering Conference
  • ASME 2007 Summer Bioengineering Conference
  • Keystone, Colorado, USA, June 20–24, 2007
  • Conference Sponsors: Bioengineering Division
  • ISBN: 0-7918-4798-5
  • Copyright © 2007 by ASME


In earlier work, we observed different patterns of disease distribution in the aortic arches of apolipoprotien E (apoE)-deficient C57BL/6 (B6) and 129/SvEv (129) mouse strains [1]. In the relatively young mice (6 mo old), fatty plaques are seen mainly in the aortic root area, extending into the right innominate artery (RIA), with very little plaque in the more distal aortic arch in the B6 strain. However, in the 129 strain, plaques are found more in the inner curvature of the aortic arch but less in the sinus area than in B6 strain (Fig. 1).

Copyright © 2007 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In