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Dissection of Porcine Ascending Aortic Media: Mechanical Characterization and Multiscale Model

[+] Author Affiliations
Sachin B. Shah, Colleen Witzenburg, Mohammad F. Hadi, Hallie P. Wagner, Janna Goodrich, Victor H. Barocas

University of Minnesota, Minneapolis, MN

Paper No. SBC2013-14610, pp. V01BT61A009; 2 pages
doi:10.1115/SBC2013-14610
From:
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5561-4
  • Copyright © 2013 by ASME

abstract

Ascending thoracic aortic aneurysm (aTAA) is a pathological condition with a high risk of dissection and rupture. Clinically, management of aTAA balances the risk of rupture with that of surgery-related complications. The risk of aneurysm rupture is known to correlate with aneurysm diameter.1,2 Aneurysms greater than 6 cm in diameter have a significantly higher risk of rupture.1 Current guidelines for intervention suggest surgical intervention for aTAA diameters greater than 5.5cm for patients without connective tissue disorders.1

Copyright © 2013 by ASME

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