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Treatment of the Aortic Coarctation: Prediction of the Hemodynamic Impact

[+] Author Affiliations
L. Goubergrits, R. Mevert, P. Yevtushenko, J. Schaller

Charité-Universitätsmedizin Berlin, Berlin, Germany

S. Meyer

Fraunhofer MEVIS, Bremen, Germany

E. Riesenkampff, T. Kuehne

Charité and German Heart Institute Berlin, Berlin, Germany

Paper No. SBC2013-14397, pp. V01BT44A002; 2 pages
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5561-4
  • Copyright © 2013 by ASME


Aortic coarctation (CoA) accounts for approximately 10% of congenital heart diseases1. CoA causing high pressure gradient can be successfully treated surgical or catheter-based. Long-term results, however, revealed decreased life expectancy associated with abnormal hemodynamics1. To develop a next-generation personalized diagnostic-prognostic tools allowing treatment optimization and thus to improve life expectance, the innovative combination of imaging science, biofluid mechanics, and computer modeling is necessary. Patient-specific computational fluid dynamics (CFD) models of the CoA based on MRI data were created to analyze pre- and post-treatment hemodynamics with a focus on pressure gradient.

Copyright © 2013 by ASME
Topics: Hemodynamics



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