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3D Computational Fluid-Structure Interaction Model of Canine Heart With Different Patch Materials for Optimal Myocardium Regeneration

[+] Author Affiliations
Heng Zuo, Glenn Gaudette, Mehmet H. Kural, Dalin Tang

Worcester Polytechnic Institute, Worcester, MA

Chun Yang

Worcester Polytechnic Institute, Worcester, MABeijing Normal University, Beijing, China

Kristen L. Billiar

Worcester Polytechnic Institute, Worcester, MAUniversity of Massachusetts Medical School, Worcester, MA

Tal Geva, Pedro J. del Nido

Children’s Hospital Boston, Harvard Medical School, Boston, MA

Paper No. SBC2013-14479, pp. V01AT13A018; 2 pages
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5560-7
  • Copyright © 2013 by ASME


Myocardial tissue regeneration techniques are being developed for the potential that viable myocardium may be regenerated to replace scar tissues in the heart or used as patch material in heart surgery [1]. The material property of the patch on which myocardium cells are placed has important impact on cell adhesion and multiplication [2]. Fluid-structure interaction (FSI) models for canine heart with patch was introduced to quantify regional flow and mechanical conditions in the patch area and investigate the influence of the different patch materials on myocardium regeneration.

Copyright © 2013 by ASME



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