Full Content is available to subscribers

Subscribe/Learn More  >

Fluid-Structure Interaction Predictions of Ascending Aorta Hemodynamics Under Tricuspid and Bicuspid Aortic Valve Flows

[+] Author Affiliations
Kai Cao, Philippe Sucosky

University of Notre Dame, Notre Dame, IN

Paper No. SBC2013-14291, pp. V01AT13A009; 2 pages
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5560-7
  • Copyright © 2013 by ASME


The bicuspid aortic valve (BAV) is the most common congenital cardiac anomaly and is present in 2–3% of the general population. As compared to the normal tricuspid aortic valve (TAV) which consists of three leaflets, the most prevalent type-I BAV morphology forms with two as a result of left-/right-coronary cusp fusion. While the BAV anatomy may not intrinsically hamper valvular function, it is associated with a spectrum of secondary aortopathy such as aortic dilation and subsequent dissection. The dilation and thinning of the ascending aorta downstream of a BAV is marked by structural wall abnormalities including smooth muscle cell depletion, elastic fiber degeneration and abnormal extracellular matrix remodeling, which localize to the convexity of the aortic wall.

Copyright © 2013 by ASME



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In