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Patient-Specific Stented Coronary Bifurcations: Numerical Analysis of Near-Wall Quantities and the Bulk Flow

[+] Author Affiliations
Claudio Chiastra, Stefano Morlacchi, Gabriele Dubini, Francesco Migliavacca

Politecnico di Milano, Milano, Italy

Diego Gallo, Umberto Morbiducci

Politecnico di Torino, Torino, Italy

Rubén Cárdenes, Ignacio Larrabide

Universitat Pompeu Fabra, Barcelona, SpainCIBER-BNN, Barcelona, Spain

Alejandro F. Frangi

Universitat Pompeu Fabra, Barcelona, SpainCIBER-BNN, Barcelona, SpainUniversity of Sheffield, Sheffield, UK

Paper No. SBC2013-14256, pp. V01AT12A002; 2 pages
doi:10.1115/SBC2013-14256
From:
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5560-7
  • Copyright © 2013 by ASME

abstract

The mechanisms and the causes of the in-stent restenosis process in coronary arteries are not fully understood. One of the most relevant phenomena, which seems to be associated to this process, is an altered hemodynamics in the stented wall region [1]. In vivo local measurements of velocities and their gradients in human coronary arteries are very difficult and can hardly be applied to successfully investigate the fluid dynamic field [1]. Alternatively, virtual models of blood flow in patient-specific coronary arteries allow the study of local fluid dynamics and the computation of the wall shear stress (WSS) and other quantities which can be related to the risk of restenosis.

Copyright © 2013 by ASME

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