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Simulation of Velocity and Concentration Fields in Artificial Kidneys

[+] Author Affiliations
Weili Li, Gang Zhao, Weiping Ding

University of Science and Technology of China, Hefei, Anhui, China

Sijie Sun

University of Washington, Seattle, WA

Dayong Gao

University of Science and Technology of China, Hefei, Anhui, ChinaUniversity of Washington, Seattle, WA

Paper No. SBC2013-14393, pp. V01AT07A015; 2 pages
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5560-7
  • Copyright © 2013 by ASME


In this work, velocity and concentration fields on both sides of blood and dialysate in artificial kidneys are simulated, not only coupling the convection and diffusion mass transfers across the hollow fiber membrane, but also considering both effects of the inlet and outlet structure of blood and dialysate. Our results show that compared to the blood velocity field, the dialysate velocity filed is more uneven; furthermore, the inlet and outlet structure of dialysate affects not only the concentration field on the dialysate side but the one on the blood side as well. Therefore, in practice, for the structure optimization of artificial kidneys, the inlet and outlet of dialysate should be focused on.

Copyright © 2013 by ASME



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