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Hemodynamics of Abdominal Aortic Aneurysm and its Clinical Relevance in Patients With Infrarenal Stent-Graft Implantation

[+] Author Affiliations
Y.-H. Lu

National Yang-Ming University Hospital, Yilan, Taiwan

G.-T. Liu, S.-H. Lin, C.-Y. Chen

National Taiwan University of Science and Technology, Taipei, Taiwan

Paper No. SBC2013-14424, pp. V01AT04A013; 2 pages
doi:10.1115/SBC2013-14424
From:
  • ASME 2013 Summer Bioengineering Conference
  • Volume 1A: Abdominal Aortic Aneurysms; Active and Reactive Soft Matter; Atherosclerosis; BioFluid Mechanics; Education; Biotransport Phenomena; Bone, Joint and Spine Mechanics; Brain Injury; Cardiac Mechanics; Cardiovascular Devices, Fluids and Imaging; Cartilage and Disc Mechanics; Cell and Tissue Engineering; Cerebral Aneurysms; Computational Biofluid Dynamics; Device Design, Human Dynamics, and Rehabilitation; Drug Delivery and Disease Treatment; Engineered Cellular Environments
  • Sunriver, Oregon, USA, June 26–29, 2013
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5560-7
  • Copyright © 2013 by ASME

abstract

In 2008 the overall rate of death attributable to cardiovascular disease, or CVD, is 244.8 per 100,000. On the basis of these mortality rate data, one American dies due to CVD on an average of every 39 seconds. Of these deaths, abdominal aortic aneurysm (AAA) accounts for 11,079 [1]. Although an estimate of the total economic burden of AAA is not available, the average cost per discharge for a ruptured AAA exceeded $93,000 in 2003 [2]. Generally, an abdominal aortic aneurysm (AAA) is an irreversible focal dilation of an artery to 1.5 times its normal diameter [3]. AAAs are characterized by the destruction of elastin and collagen in the media and adventitia, smooth muscle cell loss with thinning of the medial wall, infiltration of lymphocytes and macrophages, and neovascularization [4, 5].

Copyright © 2013 by ASME

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