Full Content is available to subscribers

Subscribe/Learn More  >

Identification of a Transversely Isotropic Material Model for White Matter in the Brain

[+] Author Affiliations
Yuan Feng, Ruth J. Okamoto, Ravi Namani, Guy M. Genin, Philip V. Bayly

Washington University, St. Louis, MO

Paper No. IMECE2012-88610, pp. 787-794; 8 pages
  • ASME 2012 International Mechanical Engineering Congress and Exposition
  • Volume 2: Biomedical and Biotechnology
  • Houston, Texas, USA, November 9–15, 2012
  • Conference Sponsors: ASME
  • ISBN: 978-0-7918-4518-9
  • Copyright © 2012 by ASME


Axonal fiber tracts in white matter of the brain form anisotropic structures. It is assumed that this structural anisotropy causes mechanical anisotropy, making white matter tissue stiffer along the axonal fiber direction. This, in turn, will affect the mechanical loading of axonal tracts during traumatic brain injury (TBI). The goal of this study is to use a combination of in-vitro tests to characterize the mechanical anisotropy of white matter and compare it to gray matter, which is thought to be structurally and mechanically isotropic. A more complete understanding of the mechanical anisotropy of brain tissue will provide more accurate information for computational simulations of brain injury.

Copyright © 2012 by ASME
Topics: Matter , Brain



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In