0

Full Content is available to subscribers

Subscribe/Learn More  >

In-Vivo Real-Time Contrast-Free Ultrasonic Blood Flow Velocity Profile Measurement

[+] Author Affiliations
G. G. Koutsouridis, N. Bijnens, F. N. van de Vosse, M. C. M. Rutten

Eindhoven University of Technology, Eindhoven, The Netherlands

P. J. Brands

ESAOTE Europe BV, Maastricht, The Netherlands

Paper No. SBC2012-80542, pp. 965-966; 2 pages
doi:10.1115/SBC2012-80542
From:
  • ASME 2012 Summer Bioengineering Conference
  • ASME 2012 Summer Bioengineering Conference, Parts A and B
  • Fajardo, Puerto Rico, USA, June 20–23, 2012
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4480-9
  • Copyright © 2012 by ASME

abstract

Recently, Ultrasonic Perpendicular Velocimetry (UPV) based algorithms, as opposed to commonly used Doppler technique (Figure 1), were applied to Radio Frequency (RF)-data acquired in an in-vitro setup [1,3]. Thus, the estimation of velocity components perpendicularly to the ultrasound beam and the simultaneous and accurate assessment of wall position and axial velocity profiles were made feasible. By integrating the measured velocity profile an accurate flow estimation was made possible. Furthermore, the ratio between the changes in flow Q(t) and the changes in cross-sectional area of the vessel A(t) was found to offer an accurate estimation of the local Pulse Wave Velocity (PWV). By combining the PWV with the diameter waveform, accurate local pressure estimation was obtained indicating that a non-invasive pressure assessment by means of ultrasound is feasible [3]. However, the abovementioned method is time consuming due to the data size and the post-processing procedure required. Additionally, the Fast Fourier Transform (FFT) on Butterworth Band Pass Filters (BPF) for vessel’s wall removal requires contrast agents dispersion in the fluid for the application of UPV. A real-time approach, of the previously described techniques, was applied [2] in-vitro using a Blood Mimicking Fluid (BMF), as contrast agent, resembling the rheological (shear thinning) and acoustical (backscattering) properties of blood and ex-vivo using BMF or contrast-free real blood implementing Wavelet Transform (WT) filtering. The use of a Graphics Processing Unit (GPU) [4], succeeded in considerable acceleration and WT [5] filtering on the rough RF-data, in improvement of the discrimination between reflections from the vessel wall and scattering from small particles. In this research the method is extended to include in-vivo measurements.

Copyright © 2012 by ASME

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In