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Negative Correlation of Wall Thickness With Wall Blood Pressure in a Patient-Specific Atherosclerotic Coronary Artery: A Case Report

[+] Author Affiliations
Biyue Liu

Monmouth University, West Long Branch, NJ

Jie Zheng, Richard Bach, Dalin Tang

Washington University School of Medicine, St. Louis, MO

Paper No. SBC2012-80039, pp. 907-908; 2 pages
  • ASME 2012 Summer Bioengineering Conference
  • ASME 2012 Summer Bioengineering Conference, Parts A and B
  • Fajardo, Puerto Rico, USA, June 20–23, 2012
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4480-9
  • Copyright © 2012 by ASME


There are two major hemodynamic stresses imposed at the blood-arterial wall interface by flowing blood: the wall shear stress (WSS) acting tangentially to the wall, and the wall pressure (WP) acting vertically to the wall. These forces influence the artery wall metabolism and correspond to the local modifications of artery wall thickness, composition, microarchitecture, and compliance [2]. The role of flow wall shear stress in atherosclerosis progression has been under intensive investigation [4], while the impact of local blood pressure on plaque progression has been under-studied.

Copyright © 2012 by ASME



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