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Investigation on a Relationship Between Hemodynamics and Wall-Thinning in an Unruptured Human Cerebral Aneurysm

[+] Author Affiliations
Yasutaka Tobe, Takanobu Yagi, Sara Takahashi, Yuki Iwabuchi, Momoko Yamanashi, Kiyotaka Iwasaki, Mitsuo Umezu

Waseda University, Tokyo, Japan

Yoshifumi Hayashi, Hirotaka Yoshida, Kazutoshi Nishitani, Yoshifumi Okada, Michihito Sugawara, Shin Hiraguchi, Toshiro Kubo, Shigemi Kitahara

Kitahara International Hospital, Hachioji, Tokyo, Japan

Paper No. SBC2012-80892, pp. 853-854; 2 pages
  • ASME 2012 Summer Bioengineering Conference
  • ASME 2012 Summer Bioengineering Conference, Parts A and B
  • Fajardo, Puerto Rico, USA, June 20–23, 2012
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4480-9
  • Copyright © 2012 by ASME


Recent studies of cerebral aneurysms are held using the blood flow simulation with patient-specific luminal geometries. In the study of development of cerebral aneurysms, wall shear stress (WSS) is focused as one of the key factors1–2. But the answer to the relationship between the extension of aneurysm and the theory of low WSS and high WSS still remains a question. One reason this question remains unsolved is because the current research about the cerebral aneurysms are held only using the vascular geometry developed from the medical images. From the intra-operative observation of cerebral aneurysms, the appearance of the cerebral aneurysm is not unified. Certain parts of the cerebral aneurysm have thin-walled structures where the blood flow of the aneurysm can be observed through the aneurysm wall. These differences in the wall structures cannot be predicted from the medical images. The purpose of this study is to see the relationship between hemodynamic patterns and thin-walled structure in human cerebral aneurysms.

Copyright © 2012 by ASME



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