0

Full Content is available to subscribers

Subscribe/Learn More  >

Prediction of the Impact of Craniospinal Compliance on the Relative Timing of Arterial and Cerebrospinal Fluid Pulsations and Perivascular Fluid Flow Into the Spinal Cord

[+] Author Affiliations
Bryn A. Martin, Nikos Stergiopulos

Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Paper No. SBC2012-80673, pp. 1201-1202; 2 pages
doi:10.1115/SBC2012-80673
From:
  • ASME 2012 Summer Bioengineering Conference
  • ASME 2012 Summer Bioengineering Conference, Parts A and B
  • Fajardo, Puerto Rico, USA, June 20–23, 2012
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4480-9
  • Copyright © 2012 by ASME

abstract

Craniospinal compliance (CC) has been hypothesized to have importance in craniospinal disorders such as hydrocephalus and syringomyelia in which tissue edema occurs. In this study we assess the impact of CC on 1) the relative timing of spinal cord blood flow (SCBF) and cerebrospinal fluid (CSF) pulsations and 2) perivascular flow (PVS) into the spinal cord (SC). A previously developed coupled model of the cardiovascular and CSF system is utilized to obtain the results. The results predict that CC can significantly alter the relative timing of arterial and CSF pulsations in the spine and total perivascular flow to the SC. CC was found to have the greatest impact on relative timing and PVF in the lumbar spine and to a lesser extent in the cervical and thoracic spine. A reduction in CC resulted in increased PVF to the SC that might help to explain tissue edema present in craniospinal disorders with reduced CC.

Copyright © 2012 by ASME

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In