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Enhancing the Biomechanical Properties of Self-Assembled, Costochondral Cell Neocartilage Through Modulation of Seeding Density and Expansion Media

[+] Author Affiliations
Meghan Murphy, Andrew Reimer, Daniel Huey, Jerry Hu, Kyriacos Athanasiou

University of California Davis, Davis, CA

Paper No. SBC2012-80357, pp. 1135-1136; 2 pages
doi:10.1115/SBC2012-80357
From:
  • ASME 2012 Summer Bioengineering Conference
  • ASME 2012 Summer Bioengineering Conference, Parts A and B
  • Fajardo, Puerto Rico, USA, June 20–23, 2012
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4480-9
  • Copyright © 2012 by ASME

abstract

Disorders of the soft tissues of the temporomandibular joint (TMJ), including the TMJ disc and cartilages, have elicited work in engineering tissue replacements; these must be able to function within the joint’s mechanically demanding environment. Such efforts are met with the challenges of 1) identifying a suitable source of donor cells and 2) expanding these cells while maintaining a phenotype that generates mechanically robust tissue.

Copyright © 2012 by ASME

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