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Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs

[+] Author Affiliations
Devin Neal, Mahmut Selman Sakar, H. Harry Asada

Massachusetts Institute of Technology, Cambridge, MA

Paper No. SBC2012-80228, pp. 1133-1134; 2 pages
  • ASME 2012 Summer Bioengineering Conference
  • ASME 2012 Summer Bioengineering Conference, Parts A and B
  • Fajardo, Puerto Rico, USA, June 20–23, 2012
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4480-9
  • Copyright © 2012 by ASME


Tissue engineered skeletal muscle constructs have and will continue to be valuable in treating, and testing various muscle injuries and diseases. However a significant drawback to numerous methods of producing 3D skeletal muscle constructs grown in vitro is that muscle cell density as a fraction of total volume or mass, is often significantly lower than muscle found in vivo. Therefore a method to increase muscle cell density within a construct is needed.

Copyright © 2012 by ASME



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