Full Content is available to subscribers

Subscribe/Learn More  >

Nanodiamond Reinforced PLLA Nanocomposites for Bone Tissue Engineering

[+] Author Affiliations
Qingwei Zhang, Yury Gogotsi, Peter I. Lelkes, Jack G. Zhou

Drexel University, Philadelphia, PA

Paper No. MSEC2012-7393, pp. 885-889; 5 pages
  • ASME 2012 International Manufacturing Science and Engineering Conference collocated with the 40th North American Manufacturing Research Conference and in participation with the International Conference on Tribology Materials and Processing
  • ASME 2012 International Manufacturing Science and Engineering Conference
  • Notre Dame, Indiana, USA, June 4–8, 2012
  • Conference Sponsors: Manufacturing Engineering Division
  • ISBN: 978-0-7918-5499-0
  • Copyright © 2012 by ASME


Nanodiamond (ND) is an attractive nanomaterial for reinforcement of biopolymers due to the ND’s superior mechanical and chemical properties, and low biotoxicity. A novel composite material has been produced for bone scaffolds utilizing the biodegradable polymer poly(L-lactic acid) (PLLA) and octadecylamine-functionalized nanodiamond (ND-ODA). Composites were prepared by admixing to a PLLA/chloroform solution chloroform suspension of ND-ODA in concentration range of 0–10% (w/w). The dispersion of ND-ODA evaluated by transmission electron microscopy (TEM) shows uniform distribution of ND-ODA in PLLA matrix. The composites were characterized by differential scanning calorimetry (DSC). DSC analysis of the composites showed no significant thermal behavior changes with the addition of ND-ODA into the polymer. Biomineralization test shows that ND-ODA can enhance the mineral deposition on scaffolds. Improved mechanical properties and good biocompatibility with enhanced biomineralization combined suggest that ND-ODA/PLLA might have potential applications for bone tissue engineering.

Copyright © 2012 by ASME
Topics: Bone , Nanocomposites



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In