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Abrupt Recruitment of Medial Collagen Fibers in the Rabbit Carotid Artery

[+] Author Affiliations
Michael R. Hill, Anne M. Robertson

University of Pittsburgh, Pittsburgh, PA

Paper No. SBC2011-53641, pp. 507-508; 2 pages
  • ASME 2011 Summer Bioengineering Conference
  • ASME 2011 Summer Bioengineering Conference, Parts A and B
  • Farmington, Pennsylvania, USA, June 22–25, 2011
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5458-7
  • Copyright © 2011 by ASME


Elastin and collagen are dominant passive load bearing proteins in the artery wall. An accepted hypothesis is that during extension of the vessel, the highly distensible elastin bears most of the load at low stretch, while increasing amounts of the less distensible medial collagen fibers uncrimp and thus bear increasing load as the overall tissue stretch increases [1]. Whether or not the collagen fibers are gradually recruited beginning at an infinitesimal stretch or at a finite stretch remains unresolved.

Copyright © 2011 by ASME



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