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Database of Rabbit Aortic Geometries for Use in Computational Flow Studies

[+] Author Affiliations
V. Peiffer, M. Rowland, P. D. Weinberg, S. J. Sherwin

Imperial College London, London, UK

Paper No. SBC2011-53469, pp. 19-20; 2 pages
doi:10.1115/SBC2011-53469
From:
  • ASME 2011 Summer Bioengineering Conference
  • ASME 2011 Summer Bioengineering Conference, Parts A and B
  • Farmington, Pennsylvania, USA, June 22–25, 2011
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5458-7
  • Copyright © 2011 by ASME

abstract

Although risk factors for atherosclerosis such as genetic predisposition and diet are systemic, the disease develops non-uniformly throughout the arterial system. Lesions preferentially occur in curved arteries and branching regions and their distribution has been observed to change with age in both humans and rabbits [1]. If local blood flow patterns play a role in the initiation of atherosclerosis, the age-related differences may be a consequence of changes in the flow characteristics.

Copyright © 2011 by ASME

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