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Modeling of Tissue Fatigue Damage in Bio-Prosthetic Heart Valve

[+] Author Affiliations
Caitlin Martin, Wei Sun

University of Connecticut, Storrs, CT

Paper No. SBC2011-53888, pp. 1217-1218; 2 pages
doi:10.1115/SBC2011-53888
From:
  • ASME 2011 Summer Bioengineering Conference
  • ASME 2011 Summer Bioengineering Conference, Parts A and B
  • Farmington, Pennsylvania, USA, June 22–25, 2011
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-5458-7
  • Copyright © 2011 by ASME

abstract

Bio-prosthetic heart valves (BHVs) with leaflets made of glutaraldehyde-treated bovine pericardium (GLBP), have been used extensively to replace diseased heart valves. BHVs display superior hemodynamics to mechanical valves and eliminate the need for anticoagulant therapy; however, they exhibit poor durability resulting from in vivo degradation and fatigue damage of the leaflets.

Copyright © 2011 by ASME

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