Full Content is available to subscribers

Subscribe/Learn More  >

Developing Brain and Heart Cells Respond Similarly to Altered Mechanical Loads

[+] Author Affiliations
Benjamen A. Filas, Philip V. Bayly, Larry A. Taber

Washington University, St. Louis, MO

Paper No. SBC2010-19029, pp. 773-774; 2 pages
  • ASME 2010 Summer Bioengineering Conference
  • ASME 2010 Summer Bioengineering Conference, Parts A and B
  • Naples, Florida, USA, June 16–19, 2010
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4403-8
  • Copyright © 2010 by ASME


Past studies have shown that the mechanical environment plays a critical role in regulating tissue development and function. For example, in the embryonic heart abnormal internal pressures cause morphological adaptation leading to aberrant morphogenesis [1]. Similarly, increasing luminal pressure in the early brain results in hyper-proliferation of the neuroepithelium [2]. Less is known, however, about how embryonic precursor cells quantitatively adapt to changes in loading, especially in vivo and across tissue types. These data would be valuable in determining the role of altered mechanical loads in congenital defects.

Copyright © 2010 by ASME
Topics: Stress , Brain



Interactive Graphics


Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In