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Study of Beloussov’s Hyper-Restoration Hypothesis for Regulation of Embryonic Heart Bending

[+] Author Affiliations
Ashok Ramasubramanian

Union College, Schenectady, NY

Larry A. Taber

Washington University, St. Louis, MO

Paper No. SBC2010-19260, pp. 63-64; 2 pages
doi:10.1115/SBC2010-19260
From:
  • ASME 2010 Summer Bioengineering Conference
  • ASME 2010 Summer Bioengineering Conference, Parts A and B
  • Naples, Florida, USA, June 16–19, 2010
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4403-8
  • Copyright © 2010 by ASME

abstract

During cardiac c-looping, an important developmental phase in early heart development, the initially straight heart tube (HT) is transformed into a c-shaped tube. Two distinct processes, ventral bending and dextral rotation, constitute c-looping. Previous research suggests that ventral bending is likely driven by forces that are intrinsic to the heart while dextral rotation is driven by forces applied by a pair of omphalomesenteric veins that flank the heart tube and a membrane called the splanchnopleure that lies on top of the heart.

Copyright © 2010 by ASME
Topics: Rotation , Membranes

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