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Design of Biomorphic Polymeric Heart Valve Prosthes by Means of FEM Modeling

[+] Author Affiliations
Adriano Zaffora, Maria Laura Costantino, Roberto Fumero

Politecnico di Milano, Milano, Italy

Joanna Stasiak, Geoff D. Moggridge

University of Cambridge, Cambridge, UK

Paper No. SBC2010-19420, pp. 187-188; 2 pages
doi:10.1115/SBC2010-19420
From:
  • ASME 2010 Summer Bioengineering Conference
  • ASME 2010 Summer Bioengineering Conference, Parts A and B
  • Naples, Florida, USA, June 16–19, 2010
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4403-8
  • Copyright © 2010 by ASME

abstract

Severe stenotic or insufficient native heart valves (nHV) must be substituted with artificial heart valve prostheses (aHV) to prevent heart failure. Nowadays, surgeons can implant two types of aHVs: mechanical aHV or bioprosthetic aHV. Mechanical aHVs, which are built up from synthetic hard materials, assure good reliability but require daily anticoagulant treatment to avoid blood cells damage. On the contrary, bioprosthetic aHVs, which are made from animal or human tissues, display better hemocompatibility but significant risk of failure due to tissue degradation. Despite current development in manufacturing of valve prostheses, long-term clinical applications claim for new generation of aHVs able to meet reliability and effectiveness requirements [2].

Copyright © 2010 by ASME

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