0

Full Content is available to subscribers

Subscribe/Learn More  >

A Pore Resistance Model and the Effect of Electrical Conductivity on Electroporation

[+] Author Affiliations
Jianbo Li, Hao Lin

Rutgers, The State University of New Jersey, Piscataway, NJ

Paper No. SBC2009-204988, pp. 957-958; 2 pages
doi:10.1115/SBC2009-204988
From:
  • ASME 2009 Summer Bioengineering Conference
  • ASME 2009 Summer Bioengineering Conference, Parts A and B
  • Lake Tahoe, California, USA, June 17–21, 2009
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4891-3
  • Copyright © 2009 by ASME

abstract

Electroporation is an elegant means to gain access to the cytoplasm, and to deliver molecules into the cell while simultaneously maintaining viability and functionality. In this technique, electric pulses are applied to transiently permeabilize the cell membrane. Biologically active agents, such as DNA, RNA, and amino acids, can then enter the cell to perform tasks such as gene and cancer therapy. Despite wide applications, electroporation faces significant challenges to achieve simultaneous high delivery efficiency and cell viability. Addressing such challenges requires the development of good fundamental understanding and a quantitative prediction capability, and the current work is a step toward this goal.

Copyright © 2009 by ASME

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging and repositioning the boxes below.

Related eBook Content
Topic Collections

Sorry! You do not have access to this content. For assistance or to subscribe, please contact us:

  • TELEPHONE: 1-800-843-2763 (Toll-free in the USA)
  • EMAIL: asmedigitalcollection@asme.org
Sign In