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Microstructurally Motivated Constitutive Models for Mouse Arteries

[+] Author Affiliations
Laura Hansen, William Wan, Rudolph Gleason

Georgia Institute of Technology, Atlanta, GA

Paper No. SBC2009-206768, pp. 577-578; 2 pages
  • ASME 2009 Summer Bioengineering Conference
  • ASME 2009 Summer Bioengineering Conference, Parts A and B
  • Lake Tahoe, California, USA, June 17–21, 2009
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4891-3
  • Copyright © 2009 by ASME


Vascular remodeling occurs as cells sense changes in their mechanical environment. Thus, quantifying the cells’ local environment in terms of stress and strain distributions is an important aspect in studies of vascular remodeling. Knowledge of the constitutive behavior of vessel will allow the local stresses and strains to be calculated given applied loads and geometry. The goal of this study is to determine material parameters for several constitutive models by fitting biaxial testing data from mouse carotid arteries cultured under different axial loading conditions [1].

Copyright © 2009 by ASME



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