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Tissue Engineered Heart Valves Develop Native-Like Collagen Architecture

[+] Author Affiliations
Martijn A. J. Cox, Jeroen Kortsmit, Carlijn V. C. Bouten, Frank P. T. Baaijens

Eindhoven University of Technology, Eindhoven, The Netherlands

Paper No. SBC2009-206236, pp. 147-148; 2 pages
doi:10.1115/SBC2009-206236
From:
  • ASME 2009 Summer Bioengineering Conference
  • ASME 2009 Summer Bioengineering Conference, Parts A and B
  • Lake Tahoe, California, USA, June 17–21, 2009
  • Conference Sponsors: Bioengineering Division
  • ISBN: 978-0-7918-4891-3
  • Copyright © 2009 by ASME

abstract

Over the last few years, research interest in tissue engineering as an alternative for current treatment and replacement strategies for cardiovascular and heart valve diseases has significantly increased. For a tissue engineered heart valve to be functional, it should be able to withstand the high pressures and flows that occur in vivo. Nature’s solution for this challenge can be found in the complex collagen fiber architecture of the native aortic valve (Fig. 1).

Copyright © 2009 by ASME

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